Get medical help if across the eight RCTs in the meta-analysis of plant-based used on the skin products, six reported no side effects and two did not specify side effects data, suggesting an overall favorable.
Ingredient
Safety not yet rated
Botanical Topicals General
A 2025 meta-analysis of eight randomized controlled trials concluded that topical plant-based preparations significantly enhanced skin hydration and overall skin elasticity compared with controls, supporting the general efficacy of botanical topical products for improving skin moisture. The same meta-analysis found no statistically significant effect of botanical preparations on TEWL, net elasticity (R5), or the ratio of elastic recovery to total deformation (R7), indicating that improvements in measured hydration and overall elasticity did not consistently translate into reduced transepidermal water loss.
Reviewed health uses
Household preparations
Safety information
Across the eight RCTs in the meta-analysis of plant-based topical products, six reported no adverse events and two did not specify adverse event data, suggesting an overall favorable short-term safety profile but also incomplete reporting. The meta-analysis did not identify serious safety signals for topical plant-based products over short-term use, but the absence of detailed adverse event reporting in some trials, and the cosmetic nature of the populations, limit conclusions about rare reactions and use in compromised skin barriers.
Get medical help if the meta-analysis did not identify serious safety signals for used on the skin plant-based products over short-term use, but the absence of detailed side effects reporting in some trials, and the.